Sins for one’s soul get cut off are issurei karet.
Intermarriage, sleeping with a niddah, etc.
And yaffa, my dad intermarried, and his son (me) “converted” (After being reared in the Reform movement) and became Orthodox. HaShem calls to Himself those whom He wishes. I defied Pew Report-style predictable outcomes. Nobody would have ever guessed in a million years that the product of such an intermarriage would become Orthodox (although many don’t consider Modern Orthodoxy or Open Orthodoxy “orthodox” enough, which bears negatively on those making these claims).