Yes “practically speaking” there is no significant difference.
But still I think it is crucially important, in order to understand the difference between the two, in a philosophical sense, that they NEVER, in truth, agree, in that:
There is a FUNDAMENTAL and highly significant difference between the two in the way they describe the very nature of the laws of the reality of existence created by HaKodesh Borchu
The fact that our perceptual and measurement capabilities happen to be limited to a certain range, in no way diminishes this deeply basic difference.
In the field of Logic a basic principle is that: An almost-truth is not a type of Truth but rather a type of Falsehood.