s2021~ meeskite means ugly or funny-looking in Yiddish.
when my <now 29 1/2 y.o.> daughter was an infant, I used to privately, affectionately call her my “zeeskite-meeskite’ –> I thought I was calling her my sweetie-cutie-mousey!! then I learned that I was actually calling my precious babe-a-la ‘sweet & ugly/funny looking’!!! :-O
I continued calling her that for a very short while thereafter, figuring: she’s sweet as anything ka’h, does have a little biggish nose that her face needed to grow into, & that it would be a good fooler/foiler against the ayin hora.
I dunno if this is coming out comprehensibly…I guess you just had to be there!