GH: (Moderna?) now being tested for younger age groups
I think they are. I am not sure how this test is being designed. I can see them testing for short-term safety. But how do you test for effectiveness given low disease rates? Either you need a huge group or maybe they are testing for some intermediate metrics, such as viral load?
Anyway, Israelis started vaccinating kids w/ medical issues without waiting for placebo-based testing. It looks more and more that real-life testing (with caution) is more effective way to get to the solution than FDA “golden standards”. It may have been OK at the beginning -Warp speed ensured that manufacturing was being set up during themonths of Phase 3, so there was no real delay. But now, there might be time to go with less-controlled tests. For those concerned, analyzing data from uncontrolled settings is still science. It has higher chance of error – but it compensates for ability to test more variations (dosage, for example) and more test cases.