Reply To: Hydroxychloroquine

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#1851954
ubiquitin
Participant

Syag

“Ubiq – is the extensive kidney damage you have seen a side effect of the covid or is the virus attacking the kidneys?”

nobody seems to know for certain. (There was just a webinar by ASN – leading nephrology group in the US, just last night!)
The prevailing thought is it is a side effect due to patient being in shock, low flow state leading to ATN (Acute tubular necrosis, sort of the similar to a heart attack but of the kidneys) most biopsies and post mortems have supported this.
BUT
I (and all colleagues IVe spoken to) have seen many many patients who’s blood pressures were not that sick (ie not in shock,) but with rapidly failing kidneys far out of proportion to their overall presentation.
the SARS-CoV-2 is known to bind to a receptor found in the kidneys (Ace2) and some theorize that it may be directly attacking that way
Another theory is that these pats seem to be hypercoaguable, menaing have a high propensity to form blood clots . could they be forming tiny blood clots int he kidneys?