In Pre-war Europe most of the jews in the Shtetls were religious, however most of the jews in the Cities were not.
In Warsaw , jews voted in general elections for their own parties and the largest vote getter was the Bund (A Non-Religious, Socialist, Anti-Zionist faction) . The Bund was also behind the Warsaw ghetto uprising (They were able to get other factions to join them which was generally impossible elsewhere because the large Aktion took place in the Summer of 1942 and the 60,000 jews remaining realized there was no other option)