To Midwesterner:
Other than her ending up being widowed, divorced, living in poverty not having children, or her own life ending early (did I leave anything out from the daf) I’m not sure there are any issues for the bas talmid chochom ending up marring a bochur who may not be the sharpest knife in the drawer. In all seriousness though, the chassan/kalah need to truly care for and respect for one another aside from reviewing their respective parents’ resumes. Its generally a good predictor but one wouldn’t expect a bas talmid chochom (aka baas Kohen) to be dating the local Am ha’Aretz (ben yisroel) from the outset unless the shadchan was himself/herself the product of such a union.