The closest to 46th Street and 2nd Ave according to Godaven.
Beit Yitzchak Ohel Sarah Synagogue (sefardi) -587 Fifth Avenue (between 47 & 48 street) New York, NY 10017 USA (212) 750-5000 – says there is Shacharis M/Th @ 8am.
Chabad of Midtown (see above) is next closest for Shacharis.
I think there are minyanim by the diamond district by the dairy cafe there – but it’d might be only Mincha.